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CS-W001157 4
Total: USD 88.00

Betamipron

  • CAS No. 3440-28-6

  • Cat. No. CS-4674
  • Purity≥98%
  • MDL No.MFCD00037293

*For research and further manufacturing use only, not for direct human use.

Betamipron|CS-4674

Structure of 3440-28-6

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General Information

  • CAS No. 3440-28-6
  • Cat. No. CS-4674
  • Purity ≥98%
  • MDL No. MFCD00037293
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₁NO₃
  • Molecular Weight 193.20
  • Synonym(s) N-Benzoyl-β-alanine
  • SMILES O=C(O)CCNC(C1=CC=CC=C1)=O

Description

Betamipron is a bench-stable, moisture-tolerant reagent designed for efficient C–H functionalization in complex molecular architectures. This electron-deficient iminium species enables direct coupling with nucleophiles under mild conditions, streamlining access to densely substituted heterocycles and advanced intermediates in medicinal chemistry workflows.

Application

Betamipron serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocyclic scaffolds. Its stable pyridine core exhibits excellent functional group tolerance and facilitates palladium-catalyzed cross-coupling reactions, supporting efficient late-stage diversification. The compound demonstrates robust bench stability and compatibility with standard purification protocols, making it well-suited for high-throughput screening campaigns and process development workflows.

Synthesis

  • Route1
    • null|null
      98-88-4
    • In-stock
      β-Alanine|CS-W020126
      107-95-9
    • ~75%
    • In-stock
      Betamipron|CS-4674
      3440-28-6

    References

    • Journal of Organometallic Chemistry, , vol. 641, # 1-2 p. 71 - 80
  • Route2
    • null|null
      69689-45-8
    • ~%
    • In-stock
      Betamipron|CS-4674
      3440-28-6

    References

    • Journal of the American Chemical Society, , vol. 127, # 49 p. 17556 - 17564
  • Route3
    • N-(2-Chloroethyl)benzamide|CS-0117057
      26385-07-9
    • ~%
    • In-stock
      Betamipron|CS-4674
      3440-28-6

    References

    • Tetrahedron, , vol. 45, # 7 p. 2183 - 2192

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   66.4
  • LogP   0.8911
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   4

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