Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1,4-Diazepan-5-one

  • CAS No. 34376-54-0

  • Cat. No. CS-W011246
  • Purity≥95%
  • MDL No.MFCD00766804

*For research and further manufacturing use only, not for direct human use.

1,4-Diazepan-5-one|CS-W011246

Structure of 34376-54-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 34376-54-0
  • Cat. No. CS-W011246
  • Purity ≥95%
  • MDL No. MFCD00766804
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₀N₂O
  • Molecular Weight 114.15
  • Synonym(s) 5-oxo-1,4-diazepan-1-ium
  • SMILES O=C1CCNCCN1

Description

1,4-Diazepan-5-one is a heterocyclic scaffold featuring a seven-membered ring with two nitrogen atoms at positions 1 and 4. This bicyclic framework imparts conformational rigidity and enhanced metabolic stability, making it a valuable building block in medicinal chemistry. The ketone functionality at position 5 enables direct derivatization through nucleophilic addition or reductive amination. The molecule exhibits favorable solubility profiles in common organic solvents and maintains stability under standard bench conditions. Its structural motif is frequently employed in the synthesis of CNS-targeted therapeutics and kinase inhibitors.

Synthesis

  • Route1

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 23 p. 5907 - 5911
  • Route2
    • null|null
      40064-34-4
    • ~76%
    • In-stock
      1,4-Diazepan-5-one|CS-W011246
      34376-54-0

    References

    • Groves,J.T.; Chambers,R.R. Journal of the American Chemical Society, 1984 , vol. 106, p. 630
  • Route3

    References

    • US2010/204214 A1, ; Page/Page column 108-109 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   41.13
  • LogP   -0.9041
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1,4-Diazepan-5-one sigma1,4-Diazepan-5-one manufacturer1,4-Diazepan-5-one price1,4-Diazepan-5-one structure1,4-Diazepan-5-one SDSbuy 1,4-Diazepan-5-one1,4-Diazepan-5-one supplier1,4-Diazepan-5-one uses1,4-Diazepan-5-one molecular weightprice of 1,4-Diazepan-5-one1,4-Diazepan-5-one chemical name formula of 1,4-Diazepan-5-one
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label