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CS-W001157 4
Total: USD 88.00

Tri(naphthalen-1-yl)phosphine

  • CAS No. 3411-48-1

  • Cat. No. CS-W011672
  • Purity≥95%
  • MDL No.MFCD00046400

*For research and further manufacturing use only, not for direct human use.

Tri(naphthalen-1-yl)phosphine|CS-W011672

Structure of 3411-48-1

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General Information

  • CAS No. 3411-48-1
  • Cat. No. CS-W011672
  • Purity ≥95%
  • MDL No. MFCD00046400
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₀H₂₁P
  • Molecular Weight 412.47
  • Synonym(s) trinaphthalen-1-ylphosphane
  • SMILES C1=CC2=C(C=C1)C(=CC=C2)P(C1=CC=CC2=C1C=CC=C2)C1=CC=CC2=C1C=CC=C2

Description

Tri(naphthalen-1-yl)phosphine is a sterically hindered, electron-rich phosphine ligand featuring three naphthalen-1-yl groups that enhance stability and solubility. This robust ligand facilitates efficient transition metal catalysis in cross-coupling reactions under mild conditions.

Application

Tri(naphthalen-1-yl)phosphine serves as a sterically hindered, electron-rich phosphine ligand that enables efficient transition-metal-catalyzed cross-coupling reactions. Its naphthyl substituents provide enhanced stability and solubility in organic media, facilitating catalyst turnover in palladium- and nickel-mediated transformations. The ligand demonstrates robust performance in Suzuki-Miyaura and Negishi couplings, particularly for challenging substrates with sterically encumbered or electron-deficient aryl halides.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P301+P310-P330-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   6.9044
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   3

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