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CS-W001157 4
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3-Fluoro-2-hydroxybenzoic acid

  • CAS No. 341-27-5

  • Cat. No. CS-W016244
  • Purity≥98%
  • MDL No.MFCD00153167

*For research and further manufacturing use only, not for direct human use.

3-Fluoro-2-hydroxybenzoic acid|CS-W016244

Structure of 341-27-5

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General Information

  • CAS No. 341-27-5
  • Cat. No. CS-W016244
  • Purity ≥98%
  • MDL No. MFCD00153167
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅FO₃
  • Molecular Weight 156.11
  • Synonym(s) Salicylic acid, 3-fluoro-
  • SMILES C1=CC=C(C(=C1C(O)=O)O)F

Application

3-Fluoro-2-hydroxybenzoic acid serves as a versatile building block for bioactive heterocycles and pharmaceutical intermediates, offering ortho-dihydroxy and fluorinated aromatic functionality. Its dual reactive sites enable straightforward derivatization via esterification, amidation, or electrophilic substitution. The compound exhibits good bench stability and facilitates efficient purification by recrystallization, making it well-suited for scalable synthesis in medicinal chemistry workflows.

Synthesis

  • Route1

    References

    • Organic and Biomolecular Chemistry, , vol. 2, # 7 p. 963 - 964
  • Route2
    • null|null
      854914-89-9
    • ~99%
    • In-stock
      3-Fluoro-2-hydroxybenzoic acid|CS-W016244
      341-27-5

    References

    • Dobler, Markus R. Organic and Biomolecular Chemistry, 2004 , vol. 2, # 7 p. 963 - 964
  • Route3

    References

    • Micklatcher, Mark L.; Cushman, Mark Synthesis, 1999 , # 11 p. 1878 - 1880

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   1.2295
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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