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Structure of 34034-87-2
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Diethyl 2-chloro-3-oxosuccinate is a reactive diester featuring a chlorine-substituted α-carbon adjacent to two carbonyl groups. This electrophilic site enables efficient alkylation and condensation reactions in synthetic pathways. The molecule's stability under standard conditions facilitates straightforward handling, making it valuable for constructing complex heterocycles and functionalized intermediates in organic synthesis.
Diethyl 2-chloro-3-oxosuccinate serves as a versatile synthon in heterocyclic synthesis, enabling efficient access to chlorinated β-keto ester derivatives. Its α-chloro ketone functionality facilitates nucleophilic substitution and condensation reactions, particularly in the construction of substituted pyrroles, furans, and other medicinally relevant scaffolds. The molecule exhibits good bench stability and compatibility with standard purification techniques, making it a practical choice for iterative synthetic campaigns in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3265
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302+H312-H314
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Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P302+P352-P304+P340-P330-P362+P364-P363-P405-P501
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Lot numbers can be found on the outside label of a product: