Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Ethyl 2-chloroacetoacetate

  • CAS No. 609-15-4

  • Cat. No. CS-W018512
  • Purity≥95%
  • MDL No.MFCD00009141

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-chloroacetoacetate|CS-W018512

Structure of 609-15-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 609-15-4
  • Cat. No. CS-W018512
  • Purity ≥95%
  • MDL No. MFCD00009141
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₉ClO₃
  • Molecular Weight 164.59
  • Synonym(s) A 21960
  • SMILES O=C(C(C(C)=O)Cl)OCC

Description

Ethyl 2-chloroacetoacetate is a versatile β-keto ester derivative featuring a chlorine-substituted acetyl moiety. This electrophilic handle enables efficient alkylation and condensation reactions in synthetic organic chemistry. The molecule exhibits enhanced reactivity compared to non-halogenated analogs, facilitating rapid access to substituted heterocycles and carbonyl-containing frameworks under mild conditions.

Application

Ethyl 2-chloroacetoacetate serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of substituted pyridines, quinolines, and other heterocyclic scaffolds via condensation and cyclization protocols. Its α-halo ketone functionality facilitates nucleophilic substitution and enolate-mediated transformations with high regiocontrol. The compound exhibits good bench stability and is readily purified by distillation or column chromatography, making it well-suited for multi-step synthesis and process-scale applications.

Synthesis

  • Route1

    References

    • Sreedhar; Reddy, P. Surendra; Madhavi Synthetic Communications, 2007 , vol. 37, # 23 p. 4149 - 4156
  • Route2

    References

    • US2008/114196 A1, ; Page/Page column 3-4 ;
  • Route3
    • null|null
      141-78-6
    • null|null
      105-39-5
    • ~%
    • In-stock
      Ethyl 2-chloroacetoacetate|CS-W018512
      609-15-4

    References

    • Antimicrobial Agents and Chemotherapy, , vol. 48, # 8 p. 3093 - 3102

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07,GHS09
Signal Word : Danger
UN#: 2920
Class : 8(3)
Packing Group : Ⅱ
Hazard Statements : H227-H302-H314-H318-H335-H400
Precautionary Statements : P210-P261-P264-P270-P271-P273-P280-P301+P330+P331-P303+P361+P353-P363-P370+P378-P391-P403+P233-P403+P235-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   43.37
  • LogP   0.7459
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Ethyl 2-chloroacetoacetate sigmaEthyl 2-chloroacetoacetate manufacturerEthyl 2-chloroacetoacetate priceEthyl 2-chloroacetoacetate structureEthyl 2-chloroacetoacetate SDSbuy Ethyl 2-chloroacetoacetateEthyl 2-chloroacetoacetate supplierEthyl 2-chloroacetoacetate usesEthyl 2-chloroacetoacetate molecular weightprice of Ethyl 2-chloroacetoacetateEthyl 2-chloroacetoacetate chemical name formula of Ethyl 2-chloroacetoacetate
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label