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Structure of 33898-90-7
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3-Oxo-3-(thiophen-2-yl)propanenitrile features a conjugated enone-nitrile system flanked by a thiophene ring, delivering enhanced stability and reactivity in heterocyclic synthesis. This electron-deficient building block integrates readily into Michael additions and cycloaddition cascades, enabling efficient access to functionalized thienyl-containing scaffolds under mild conditions.
3-Oxo-3-(thiophen-2-yl)propanenitrile serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted thiophene derivatives via cycloaddition and condensation reactions. Its α,β-unsaturated nitrile motif facilitates Michael additions and nucleophilic functionalization, while the ketone group supports enolization and subsequent cyclizations. Bench-stable and readily purified by recrystallization, it functions effectively in multi-step sequences for pharmaceutical and agrochemical scaffold elaboration.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: