Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Oxo-3-(thiophen-2-yl)propanenitrile

  • CAS No. 33898-90-7

  • Cat. No. CS-W018118
  • Purity≥98%
  • MDL No.MFCD00052586

*For research and further manufacturing use only, not for direct human use.

3-Oxo-3-(thiophen-2-yl)propanenitrile|CS-W018118

Structure of 33898-90-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 33898-90-7
  • Cat. No. CS-W018118
  • Purity ≥98%
  • MDL No. MFCD00052586
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅NOS
  • Molecular Weight 151.18
  • Synonym(s) 3-OXO-3-THIOPHEN-2-YL-PROPIONITRILE
  • SMILES O=C(CC#N)C1=CC=CS1

Description

3-Oxo-3-(thiophen-2-yl)propanenitrile features a conjugated enone-nitrile system flanked by a thiophene ring, delivering enhanced stability and reactivity in heterocyclic synthesis. This electron-deficient building block integrates readily into Michael additions and cycloaddition cascades, enabling efficient access to functionalized thienyl-containing scaffolds under mild conditions.

Application

3-Oxo-3-(thiophen-2-yl)propanenitrile serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted thiophene derivatives via cycloaddition and condensation reactions. Its α,β-unsaturated nitrile motif facilitates Michael additions and nucleophilic functionalization, while the ketone group supports enolization and subsequent cyclizations. Bench-stable and readily purified by recrystallization, it functions effectively in multi-step sequences for pharmaceutical and agrochemical scaffold elaboration.

Synthesis

  • Route1

    References

    • Park, Ahbyeol; Lee, Sunwoo Organic Letters, 2012 , vol. 14, # 4 p. 1118 - 1121
  • Route2
    • In-stock
      2-Thiophenemethanol|CS-0022380
      636-72-6
    • null|null
      75-05-8
    • ~82%
    • In-stock
      3-Oxo-3-(thiophen-2-yl)propanenitrile|CS-W018118
      33898-90-7

    References

    • Shen, Jiaxuan; Yang, Dejun; Liu, Yuxiao; Qin, Shuangshuang; Zhang, Jingwu; Sun, Jiangkai; Liu, Chunhui; Liu, Chaoyang; Zhao, Xiaomei; Chu, Changhu; Liu, Renhua Organic Letters, 2014 , vol. 16, # 2 p. 350 - 353
  • Route3
    • null|null
      75-05-8
    • (1H-benzo[d][1,2,3]triazol-1-yl)(thiophen-2-yl)methanone|CS-0318172
      301164-69-2
    • ~94%
    • In-stock
      3-Oxo-3-(thiophen-2-yl)propanenitrile|CS-W018118
      33898-90-7

    References

    • Katritzky, Alan R.; Abdel-Fattah, Ashraf A. A.; Wang, Mingyi Journal of Organic Chemistry, 2003 , vol. 68, # 12 p. 4932 - 4934

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H318
Precautionary Statements : P264-P270-P280-P330-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   40.86
  • LogP   1.84448
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3-Oxo-3-(thiophen-2-yl)propanenitrile sigma3-Oxo-3-(thiophen-2-yl)propanenitrile manufacturer3-Oxo-3-(thiophen-2-yl)propanenitrile price3-Oxo-3-(thiophen-2-yl)propanenitrile structure3-Oxo-3-(thiophen-2-yl)propanenitrile SDSbuy 3-Oxo-3-(thiophen-2-yl)propanenitrile3-Oxo-3-(thiophen-2-yl)propanenitrile supplier3-Oxo-3-(thiophen-2-yl)propanenitrile uses3-Oxo-3-(thiophen-2-yl)propanenitrile molecular weightprice of 3-Oxo-3-(thiophen-2-yl)propanenitrile3-Oxo-3-(thiophen-2-yl)propanenitrile chemical name formula of 3-Oxo-3-(thiophen-2-yl)propanenitrile
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label