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CS-W001157 4
Total: USD 88.00

(+)-Biotin-ONP

  • CAS No. 33755-53-2

  • Cat. No. CS-0116311
  • Molecule weight365.40
  • Purity≥97%
  • MDL No.MFCD15141972

*For research and further manufacturing use only, not for direct human use.

(+)-Biotin-ONP|CS-0116311

Structure of 33755-53-2

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General Information

  • CAS No. 33755-53-2
  • Cat. No. CS-0116311
  • Purity ≥97%
  • MDL No. MFCD15141972
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₉N₃O₅S
  • Molecular Weight 365.40
  • Synonym(s) (+)-Biotin 4-nitrophenyl ester
  • SMILES O=C(OC1=CC=C([N+]([O-])=O)C=C1)CCCC[C@@H]2SC[C@]([C@]2([H])N3)([H])NC3=O

Description

1,3-Bis(5-bromo-2-thienyl)-5,7-bis(2-ethylhexyl)-4H,8H-benzo[1,2-c:4,5-c]dithiophene-4,8-dione (BDD), a strong electron accepting molecule, can be used in the fabrication of non-fullerene polymeric solar cells. It can also be used in the synthesis of a new conjugated polymer, 5,7-bis(2- ethylhexyl)benzo[1,2-c:4,5-c]dithiophene-4,8-dione (PBDTBDD).

Application

(+)-Biotin-ONP serves as a stable, bench-ready biotinylating agent that enables efficient conjugation of biotin to primary amines under mild conditions. Its ONP (o-nitrophenyl) ester moiety offers enhanced hydrolytic stability compared to traditional NHS esters, facilitating clean labeling with minimal side reactions. Ideal for protein and peptide derivatization, it functions reliably in standard biochemical workflows and supports downstream affinity purification or detection applications.

Synthesis

  • Route1
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    • ~%
    • In-stock
      (+)-Biotin-ONP|CS-0116311
      33755-53-2

    References

    • Journal of the American Chemical Society, , vol. 99, # 1 p. 235 - 239
  • Route2

    References

    • Journal of the American Chemical Society, , vol. 99, # 1 p. 235 - 239
  • Route3

    References

    • Journal of the American Chemical Society, , vol. 99, # 1 p. 235 - 239

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   110.57
  • LogP   2.226
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   7

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