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CS-W001157 4
Total: USD 88.00

4-Bromo-2-nitroanisole

  • CAS No. 33696-00-3

  • Cat. No. CS-W009144
  • Purity≥98%
  • MDL No.MFCD00055529

*For research and further manufacturing use only, not for direct human use.

4-Bromo-2-nitroanisole|CS-W009144

Structure of 33696-00-3

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General Information

  • CAS No. 33696-00-3
  • Cat. No. CS-W009144
  • Purity ≥98%
  • MDL No. MFCD00055529
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrNO₃
  • Molecular Weight 232.03
  • Synonym(s) 4-Bromo-1-methoxy-2-nitrobenzene
  • SMILES O=[N+](C1=CC(Br)=CC=C1OC)[O-]

Description

4-Bromo-2-nitroanisole features a strategically positioned bromine atom and electron-deficient nitro group flanking a methoxy-substituted aromatic ring. This combination enables direct functionalization in cross-coupling reactions, while the methoxy group enhances solubility and stability under standard conditions.

Application

4-Bromo-2-nitroanisole serves as a versatile building block in medicinal chemistry and cross-coupling synthesis, enabling efficient access to substituted aromatic scaffolds. The bromo group facilitates palladium-catalyzed coupling reactions, while the nitro and methoxy functionalities provide orthogonal reactivity for sequential transformations. Its bench-stable nature and ease of purification support reliable integration into multi-step syntheses.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   52.37
  • LogP   2.3659
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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