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Structure of 33421-39-5
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2-Phenylpyridine-3-carboxylic acid features a rigid, planar architecture integrating an electron-deficient pyridine core with a phenyl ring and a carboxylic acid group. This combination enables strong coordination to metal centers, making it valuable in constructing luminescent complexes and functional materials.
2-Phenylpyridine-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling efficient construction of bioactive heterocycles. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions under standard conditions. The ortho-phenylpyridine motif provides structural rigidity and favorable π-stacking interactions, enhancing target binding affinity in kinase inhibitors and other pharmaceutical scaffolds. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step syntheses requiring functional group compatibility and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: