Fmoc-(R)-3-amino-4-(4-biphenyl)butanoic acid

Name: Fmoc-(R)-3-amino-4-(4-biphenyl)butanoic acid
Brand: ChemScene
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CAS No. 332062-10-9
Cat. No. CS-0149794
Purity≥98%
MDL No.MFCD02094567

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Fmoc-(R)-3-amino-4-(4-biphenyl)butanoic acid|CS-0149794

Structure of 332062-10-9

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General Information

CAS No. 332062-10-9
Cat. No. CS-0149794
Purity ≥98%
MDL No. MFCD02094567
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃₁H₂₇NO₄
Molecular Weight 477.55
Synonym(s) N-BETA-(9-FLUORENYLMETHOXYCARBONYL)-D-HOMO(4,4-DIPHENYL)ALANINE
SMILES O=C(O)C[C@@H](NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)C(C4=CC=CC=C4)C5=CC=CC=C5

Description

Fmoc-(R)-3-amino-4-(4-biphenyl)butanoic acid is a specialized amino acid derivative featuring a biphenyl-containing side chain and an Fmoc protecting group. This structure enhances solubility and stability during peptide synthesis, enabling efficient incorporation into complex sequences. The para-biphenyl moiety imparts rigidity and hydrophobic character, useful for modulating peptide conformation and membrane interactions.

Application

Fmoc-(R)-3-amino-4-(4-biphenyl)butanoic acid serves as a valuable building block for peptide synthesis, enabling the incorporation of a hydrophobic, rigid biphenyl-containing side chain. The Fmoc group provides orthogonal protection for the amine, while the carboxylic acid facilitates standard coupling reactions. This compound exhibits bench stability, good solubility in common organic solvents, and functional group tolerance, making it well-suited for solid-phase and solution-phase peptide methodologies.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

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Computational Chemistry Data

TPSA 75.63
LogP 6.2005
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 8

Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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Fmoc-(R)-3-amino-4-(4-biphenyl)butanoic acid

CAS No. 332062-10-9

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