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CS-W001157 4
Total: USD 88.00

1,2-bis(4-fluorophenyl)hydrazine Cabozantinib Impurity

  • CAS No. 332-06-9

  • Cat. No. CS-0166338
  • Purity≥98%
  • MDL No.MFCD27949518

*For research and further manufacturing use only, not for direct human use.

1,2-bis(4-fluorophenyl)hydrazine  Cabozantinib Impurity|CS-0166338

Structure of 332-06-9

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General Information

  • CAS No. 332-06-9
  • Cat. No. CS-0166338
  • Purity ≥98%
  • MDL No. MFCD27949518
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₀F₂N₂
  • Molecular Weight 220.22
  • Synonym(s) 1,2-Bis(4-fluorophenyl)hydrazine
  • SMILES FC1=CC=C(NNC2=CC=C(F)C=C2)C=C1

Synthesis

  • Route1
    • null|null
      332-07-0
    • ~%
    • 1,2-bis(4-fluorophenyl)hydrazine  Cabozantinib Impurity|CS-0166338
      332-06-9

    References

    • Gilbert, Adam M.; Failli, Amedeo; Shumsky, Jay; Yang, Youjun; Severin, Anatoly; Singh, Guy; Hu, William; Keeney, David; Petersen, Peter J.; Katz, Alan H. Journal of Medicinal Chemistry, 2006 , vol. 49, # 20 p. 6027 - 6036
  • Route2
    • null|null
      371-40-4
    • ~%
    • 1,2-bis(4-fluorophenyl)hydrazine  Cabozantinib Impurity|CS-0166338
      332-06-9

    References

    • Mitchell,P.J.; Phillips,L. Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1974 , p. 109 - 118
  • Route3
    • null|null
      326-04-5
    • ~%
    • 1,2-bis(4-fluorophenyl)hydrazine  Cabozantinib Impurity|CS-0166338
      332-06-9

    References

    • Olah et al. Acta Chimica Academiae Scientiarum Hungaricae, 1955 , vol. 7, p. 71,82

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   24.06
  • LogP   3.4038
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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