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CS-W001157 4
Total: USD 88.00

4-Phenyloxazol-2-amine

  • CAS No. 33119-65-2

  • Cat. No. CS-0046180
  • Purity≥97%
  • MDL No.MFCD13189375

*For research and further manufacturing use only, not for direct human use.

4-Phenyloxazol-2-amine|CS-0046180

Structure of 33119-65-2

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General Information

  • CAS No. 33119-65-2
  • Cat. No. CS-0046180
  • Purity ≥97%
  • MDL No. MFCD13189375
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈N₂O
  • Molecular Weight None
  • Synonym(s) 4-Phenyl-oxazol-2-ylaMine
  • SMILES NC1=NC(C2=CC=CC=C2)=CO1

Description

4-Phenyloxazol-2-amine features a fused oxazol ring bearing a phenyl substituent and a primary amine at the 2-position. This scaffold delivers enhanced solubility and stability under standard conditions, enabling direct incorporation into bioactive molecule designs. The electron-rich heterocycle facilitates coupling reactions in medicinal chemistry workflows.

Application

4-Phenyloxazol-2-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to oxazole-based scaffolds. Its amine functionality facilitates direct derivatization and conjugation, while the phenyl-substituted oxazole core exhibits good bench stability and compatibility with standard synthetic transformations. The compound functions effectively in coupling reactions and serves as a key intermediate for bioactive molecule construction.

Synthesis

  • Route1
    • null|null
      70-11-1
    • In-stock
      Urea|CS-B1800
      57-13-6
    • ~88%
    • In-stock
      4-Phenyloxazol-2-amine|CS-0046180
      33119-65-2

    References

    • Singh, Balvant S.; Lobo, Hyacintha R.; Pinjari, Dipak V.; Jarag, Krishna J.; Pandit, Aniruddha B.; Shankarling, Ganapati S. Ultrasonics Sonochemistry, 2013 , vol. 20, # 2 p. 633 - 639
  • Route2

    References

    • Crank, George; Khan, Humaid R. Australian Journal of Chemistry, 1985 , vol. 38, # 3 p. 447 - 458
  • Route3
    • 2-Oxo-2-phenylethyl acetate|CS-W017335
      2243-35-8
    • ~%
    • In-stock
      4-Phenyloxazol-2-amine|CS-0046180
      33119-65-2

    References

    • Crank, George; Khan, Humaid R. Australian Journal of Chemistry, 1985 , vol. 38, # 3 p. 447 - 458

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.05
  • LogP   1.9238
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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