Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-Bromo-3-methyl-5-(trifluoromethyl)benzene

  • CAS No. 86845-28-5

  • Cat. No. CS-W012831
  • Purity≥98%
  • MDL No.MFCD01631585

*For research and further manufacturing use only, not for direct human use.

1-Bromo-3-methyl-5-(trifluoromethyl)benzene|CS-W012831

Structure of 86845-28-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 86845-28-5
  • Cat. No. CS-W012831
  • Purity ≥98%
  • MDL No. MFCD01631585
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆BrF₃
  • Molecular Weight 239.03
  • Synonym(s) 3-Bromo-5-(trifluoromethyl)toluene
  • SMILES FC(C1=CC(C)=CC(Br)=C1)(F)F

Description

1-Bromo-3-methyl-5-(trifluoromethyl)benzene features a trifluoromethyl group that imparts enhanced metabolic stability and lipophilicity, while the bromine serves as a reactive handle for cross-coupling transformations. The meta-substituted methyl and trifluoromethyl groups create a sterically defined, electron-deficient aromatic core ideal for palladium-catalyzed reactions. This compound enables efficient access to complex fluorinated scaffolds in medicinal chemistry and materials synthesis.

Application

1-Bromo-3-methyl-5-(trifluoromethyl)benzene serves as a versatile aryl halide building block for palladium-catalyzed cross-coupling reactions, including Suzuki, Stille, and Negishi couplings. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the methyl substituent provides steric and electronic modulation. Its bench-stable nature and compatibility with diverse reaction conditions enable efficient construction of complex aromatic scaffolds relevant to agrochemical and pharmaceutical development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   0
  • LogP   3.77632
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 86845-28-5 sigma86845-28-5 manufacturer86845-28-5 price86845-28-5 structure86845-28-5 SDSbuy 86845-28-586845-28-5 supplier86845-28-5 uses86845-28-5 molecular weightprice of 86845-28-586845-28-5 chemical name formula of 86845-28-5
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label