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Structure of 33105-81-6
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2-Amino-3,3-dimethylbutanoic acid features a sterically hindered tertiary carbon adjacent to the carboxyl group, enhancing its metabolic stability. This structural motif enables robust incorporation into peptide sequences without racemization, making it valuable for synthetic peptide applications requiring resistance to enzymatic degradation.
2-Amino-3,3-dimethylbutanoic acid serves as a valuable building block in peptide synthesis and medicinal chemistry, offering a sterically hindered α-amino acid scaffold with enhanced metabolic stability. Its tertiary β-carbon facilitates resistance to enzymatic degradation while maintaining compatibility with standard coupling protocols. The molecule exhibits good bench stability and simplifies purification due to its crystalline nature and defined pKa profile, enabling efficient incorporation into complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: