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CS-W001157 4
Total: USD 88.00

Fmoc-D-Tle-OH

  • CAS No. 198543-64-5

  • Cat. No. CS-0101040
  • Purity≥97%
  • MDL No.MFCD00065650

*For research and further manufacturing use only, not for direct human use.

Fmoc-D-Tle-OH|CS-0101040

Structure of 198543-64-5

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General Information

  • CAS No. 198543-64-5
  • Cat. No. CS-0101040
  • Purity ≥97%
  • MDL No. MFCD00065650
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₂₃NO₄
  • Molecular Weight 353.41
  • Synonym(s) Fmoc-D-α-t-butylglycine
  • SMILES CC(C)(C)[C@H](C(O)=O)NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O

Description

Fmoc-D-Tle-OH is a chiral building block featuring a D-configured threonine derivative with a fluorenylmethoxycarbonyl (Fmoc) protecting group. This stable, bench-ready reagent facilitates efficient peptide synthesis through orthogonal protection strategies, enabling selective coupling and facile deprotection under mild conditions.

Synthesis

  • Route1
    • null|null
      750594-89-9
    • ~%
    • In-stock
      Fmoc-D-Tle-OH|CS-0101040
      198543-64-5

    References

    • Organic Letters, , vol. 6, # 16 p. 2801 - 2804
  • Route2
    • In-stock
      Fmoc-Osu Amino acid impurity|CS-1733136
      82911-69-1
    • (R)-2-amino-3,3-dimethylbutanoic acid hydrochloride|CS-0441091
      112720-39-5
    • ~80%
    • In-stock
      Fmoc-D-Tle-OH|CS-0101040
      198543-64-5

    References

    • Organic letters, , vol. 2, # 6 p. 867 - 870
  • Route3
    • Fmoc-OH Amino acid impurity|CS-1733148
      24324-17-2
    • ~%
    • In-stock
      Fmoc-D-Tle-OH|CS-0101040
      198543-64-5

    References

    • Organic Letters, , vol. 6, # 16 p. 2801 - 2804

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   4.0244
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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