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CS-W001157 4
Total: USD 88.00

4-(Boc-amino)benzeneboronic acid pinacol ester

  • CAS No. 330793-01-6

  • Cat. No. CS-W000913
  • Purity≥96%
  • MDL No.MFCD02179439

*For research and further manufacturing use only, not for direct human use.

4-(Boc-amino)benzeneboronic acid pinacol ester|CS-W000913

Structure of 330793-01-6

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General Information

  • CAS No. 330793-01-6
  • Cat. No. CS-W000913
  • Purity ≥96%
  • MDL No. MFCD02179439
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₂₆BNO₄
  • Molecular Weight 319.21
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NC1=CC=C(B2OC(C)(C)C(C)(C)O2)C=C1

Description

4-(Boc-amino)benzeneboronic acid pinacol ester combines a boronate handle with a protected amine for streamlined coupling in Suzuki-Miyaura reactions. The Boc group ensures stability and ease of deprotection, while the pinacol ester enhances solubility and shelf life under standard conditions.

Application

4-(Boc-amino)benzeneboronic acid pinacol ester serves as a stable, bench-ready building block for Suzuki-Miyaura cross-coupling reactions. The Boc-protected amine and pinacol boronate ester groups offer orthogonal functionality, enabling sequential transformations in complex molecule synthesis. Its high stability, ease of handling, and compatibility with diverse reaction conditions make it ideal for constructing biaryl scaffolds in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   56.79
  • LogP   3.3328
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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