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Structure of 3298-16-6
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5-Methylpiperidin-2-one is a nitrogen-containing heterocycle featuring a ketone at the 2-position and a methyl group at the 5-position. This scaffold imparts enhanced lipophilicity and metabolic stability, making it valuable in medicinal chemistry for constructing bioactive molecules with improved membrane permeability and pharmacokinetic profiles.
5-Methylpiperidin-2-one serves as a versatile scaffold in medicinal chemistry, enabling efficient access to nitrogen-containing heterocycles through standard functionalization. Its amide functionality and adjacent stereogenic center facilitate diverse transformations, including reductive amination and nucleophilic substitution, while offering good bench stability and compatibility with common reaction conditions. The molecule functions effectively as a building block for bioactive compounds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: