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CS-W001157 4
Total: USD 88.00

3,5-Di(trifluoromethyl)aniline

  • CAS No. 328-74-5

  • Cat. No. CS-W009500
  • Purity≥98%
  • MDL No.MFCD00000394

*For research and further manufacturing use only, not for direct human use.

3,5-Di(trifluoromethyl)aniline|CS-W009500

Structure of 328-74-5

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General Information

  • CAS No. 328-74-5
  • Cat. No. CS-W009500
  • Purity ≥98%
  • MDL No. MFCD00000394
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅F₆N
  • Molecular Weight None
  • Synonym(s) None
  • SMILES NC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1

Description

3,5-Bis(trifluoromethyl)aniline was used in the synthesis of:N-[2-hydroxy-1-naphthylidene]-3, 5-bis(trifluoromethyl)aniline, Schiffs base5,7-bis(trifluoromethyl)anilineN-1-phenylethyl-3,5-bis(trifluoromethyl)aniline via titanium-catalyzed hydroamination reactionN,N-bis[3,5-bis(tri-fluoromethyl)phenyl]thiourea, organocatalyst

Synthesis

  • Route1

    References

    • Lee, Dae-Yon; Hartwig, John F. Organic Letters, 2005 , vol. 7, # 6 p. 1169 - 1172
  • Route2
    • In-stock
      1-Nitro-3,5-bis(trifluoromethyl)benzene|CS-W012526
      328-75-6
    • ~64%
    • null|null
      75092-05-6
    • In-stock
      3,5-Di(trifluoromethyl)aniline|CS-W009500
      328-74-5

    References

    • Journal of Organic Chemistry USSR (English Translation), , vol. 16, p. 1031 - 1038 Zhurnal Organicheskoi Khimii, , vol. 16, # 6 p. 1194 - 1202
  • Route3
    • In-stock
      1-Bromo-3,5-bis(trifluoromethyl)benzene|CS-D0806
      328-70-1
    • ~62%
    • null|null
      32707-86-1
    • In-stock
      3,5-Di(trifluoromethyl)aniline|CS-W009500
      328-74-5

    References

    • Vo, Giang D.; Hartwig, John F. Journal of the American Chemical Society, 2009 , vol. 131, # 31 p. 11049 - 11061

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   3.3064
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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