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Structure of 3273-14-1
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2-(1H-1,2,4-Triazol-1-yl)ethan-1-ol features a polar triazole moiety linked to a hydroxyl-bearing ethylene tether, enabling robust hydrogen bonding and enhanced solubility in aqueous and protic solvents. This combination supports its utility in medicinal chemistry scaffolds and ligand design.
2-(1H-1,2,4-Triazol-1-yl)ethan-1-ol serves as a versatile building block in medicinal chemistry, enabling the introduction of a polar, hydrogen-bond-capable triazolylethanol moiety. Its hydroxyl group facilitates further functionalization via esterification or ether formation, while the 1,2,4-triazole ring provides metabolic stability and enhanced solubility. The compound exhibits good bench stability and is compatible with standard coupling protocols, making it valuable for constructing bioactive heterocyclic scaffolds and fragment libraries.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: