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Structure of 28711-29-7
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2-(1H-1,2,4-Triazol-1-yl)acetic acid features a triazolyl moiety linked to a carboxylic acid group, enabling versatile conjugation in bioconjugation and medicinal chemistry. This bench-stable compound integrates readily into peptide and small-molecule scaffolds, offering enhanced solubility and targeted functionalization through the electron-rich triazole ring.
2-(1H-1,2,4-Triazol-1-yl)acetic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of triazole-containing bioactive molecules. Its carboxylic acid functionality facilitates amide bond formation and conjugation reactions, while the 1,2,4-triazole ring provides metabolic stability and hydrogen-bonding capacity. The compound exhibits good bench stability and is compatible with standard peptide coupling protocols, making it well-suited for library synthesis and structure–activity studies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: