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CS-W001157 4
Total: USD 88.00

1-(4-Bromophenyl)imidazolidine-2,4-dione

  • CAS No. 32549-34-1

  • Cat. No. CS-0697414
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-(4-Bromophenyl)imidazolidine-2,4-dione|CS-0697414

Structure of 32549-34-1

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General Information

  • CAS No. 32549-34-1
  • Cat. No. CS-0697414
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇BrN₂O₂
  • Molecular Weight 255.07
  • Synonym(s) None
  • SMILES BrC1=CC=C(C=C1)N1CC(=O)NC1=O

Description

1-(4-Bromophenyl)imidazolidine-2,4-dione features a brominated aromatic ring integrated into a rigid imidazolidinedione scaffold, enhancing electronic modulation and metabolic stability. This structural motif serves as a key pharmacophore in kinase inhibitor design and bioactive heterocycle synthesis, offering robustness under standard bench conditions and compatibility with transition-metal-catalyzed transformations.

Application

1-(4-Bromophenyl)imidazolidine-2,4-dione serves as a versatile building block in medicinal chemistry, enabling the synthesis of biologically active heterocycles through standard coupling and functionalization reactions. Its brominated aryl group facilitates palladium-catalyzed cross-couplings, while the imidazolidinedione core provides stability and compatibility with diverse reaction conditions. The compound exhibits good bench stability and ease of purification, making it well-suited for scalable synthesis and intermediate development in API discovery workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   49.41
  • LogP   1.5053
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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