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CS-W001157 4
Total: USD 88.00

4,7-Dimethyl-1,10-phenanthroline

  • CAS No. 3248-05-3

  • Cat. No. CS-W004562
  • Purity≥98%
  • MDL No.MFCD00004979

*For research and further manufacturing use only, not for direct human use.

4,7-Dimethyl-1,10-phenanthroline|CS-W004562

Structure of 3248-05-3

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General Information

  • CAS No. 3248-05-3
  • Cat. No. CS-W004562
  • Purity ≥98%
  • MDL No. MFCD00004979
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₂N₂
  • Molecular Weight None
  • Synonym(s) 4,7-Dimethyl-o-phenanthroline
  • SMILES CC1=CC=NC2=C(N=CC=C3C)C3=CC=C21

Description

4,7-Dimethyl-1,10-phenanthroline is a bench-stable, electron-rich heteroaromatic ligand featuring two methyl groups at the 4 and 7 positions. This substitution pattern enhances solubility in organic media while maintaining strong metal-chelating capacity. The molecule integrates readily into coordination complexes, particularly with transition metals such as iron and copper, enabling efficient catalytic systems. Its steric profile supports selective binding in redox-active applications.

Application

4,7-Dimethyl-1,10-phenanthroline serves as a robust bidentate ligand in transition metal catalysis, particularly in palladium- and copper-mediated cross-coupling reactions. Its methyl substituents enhance solubility and steric profile, improving catalyst stability and enabling efficient coupling with aryl halides and pseudohalides. The ligand demonstrates excellent bench stability, simplifies purification, and functions reliably across diverse reaction conditions.

Synthesis

  • Route1
    • In-stock
      4-Methylquinolin-8-amine|CS-0152931
      62748-01-0
    • null|null
      78-94-4
    • ~%
    • In-stock
      4,7-Dimethyl-1,10-phenanthroline|CS-W004562
      3248-05-3

    References

    • Journal of Organic Chemistry, , vol. 20, p. 1330,1335
  • Route2
    • null|null
      78-94-4
    • null|null
      95-54-5
    • ~35%
    • In-stock
      4,7-Dimethyl-1,10-phenanthroline|CS-W004562
      3248-05-3

    References

    • Butt, Graeme; Topsom, Ronald D. Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 641 - 642
  • Route3

    References

    • Journal of the American Chemical Society, , vol. 70, p. 3994

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   3.39984
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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