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CS-W001157 4
Total: USD 88.00

2-(piperidin-1-yl)acetic acid

  • CAS No. 3235-67-4

  • Cat. No. CS-0067848
  • Purity≥97%
  • MDL No.MFCD00461042

*For research and further manufacturing use only, not for direct human use.

2-(piperidin-1-yl)acetic acid|CS-0067848

Structure of 3235-67-4

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General Information

  • CAS No. 3235-67-4
  • Cat. No. CS-0067848
  • Purity ≥97%
  • MDL No. MFCD00461042
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₃NO₂
  • Molecular Weight 143.18
  • Synonym(s) Piperidinoacetic acid
  • SMILES O=C(O)CN1CCCCC1

Description

2-(piperidin-1-yl)acetic acid features a piperidine ring linked via a methylene spacer to a carboxylic acid group, combining basic nitrogen functionality with moderate lipophilicity. This scaffold integrates readily into bioactive molecules, serving as a key building block in medicinal chemistry for modulating solubility and target affinity.

Application

2-(Piperidin-1-yl)acetic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive scaffolds through amide bond formation and derivatization at the carboxylic acid terminus. The piperidinyl group provides a basic nitrogen for salt formation and enhanced solubility, while the acetic acid moiety facilitates conjugation in peptide-like architectures. Its bench-stable nature and compatibility with standard coupling protocols make it well-suited for iterative synthesis workflows in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H318
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   40.54
  • LogP   0.5569
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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