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CS-W001157 4
Total: USD 88.00

1-(2-Hydroxyethyl)piperidine

  • CAS No. 3040-44-6

  • Cat. No. CS-W013444
  • Purity≥95%
  • MDL No.MFCD00006512

*For research and further manufacturing use only, not for direct human use.

1-(2-Hydroxyethyl)piperidine|CS-W013444

Structure of 3040-44-6

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General Information

  • CAS No. 3040-44-6
  • Cat. No. CS-W013444
  • Purity ≥95%
  • MDL No. MFCD00006512
  • Storage 4°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₅NO
  • Molecular Weight None
  • Synonym(s) None
  • SMILES OCCN1CCCCC1

Description

1-(2-Hydroxyethyl)piperidine (1-Piperidineethanol) has been used as the base quencher to determine the efficiency of the decomposition of photoacid generators.

Application

1-(2-Hydroxyethyl)piperidine serves as a versatile bifunctional building block in medicinal chemistry, combining a piperidine nitrogen for basicity and solubility with a primary alcohol for further derivatization. It facilitates the construction of complex heterocyclic scaffolds and enables efficient conjugation via esterification or ether formation. The compound exhibits good bench stability and compatibility with standard synthetic protocols, supporting its use in multi-step synthesis and lead optimization workflows.

Synthesis

  • Route1
    • null|null
      110-89-4
    • null|null
      540-51-2
    • ~10%
    • In-stock
      1-(2-Hydroxyethyl)piperidine|CS-W013444
      3040-44-6

    References

    • EVOTEC NEUROSCIENCES GMBH Patent: WO2009/121812 A1, 2009 ; Location in patent: Page/Page column 71 ; WO 2009/121812 A1
  • Route2
    • null|null
      58583-90-7
    • ~83%
    • In-stock
      1-(2-Hydroxyethyl)piperidine|CS-W013444
      3040-44-6

    References

    • Kuriyama, Wataru; Matsumoto, Takaji; Ogata, Osamu; Ino, Yasunori; Aoki, Kunimori; Tanaka, Shigeru; Ishida, Kenya; Kobayashi, Tohru; Sayo, Noboru; Saito, Takao Organic Process Research and Development, 2012 , vol. 16, # 1 p. 166 - 171
  • Route3
    • Ethyl 1-piperidineacetate|CS-0127986
      23853-10-3
    • ~%
    • In-stock
      1-(2-Hydroxyethyl)piperidine|CS-W013444
      3040-44-6

    References

    • Journal of the American Chemical Society, , vol. 69, p. 3039 Journal of the American Chemical Society, , vol. 70, p. 3121

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H302
Precautionary Statements : P210-P264-P270-P280-P330-P370+P378-P403-P501

Quality Control

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Computational Chemistry Data

  • TPSA   23.47
  • LogP   0.4646
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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