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CS-W001157 4
Total: USD 88.00

6-Methylnicotinic acid

  • CAS No. 3222-47-7

  • Cat. No. CS-W008333
  • Purity≥98%
  • MDL No.MFCD00006341

*For research and further manufacturing use only, not for direct human use.

6-Methylnicotinic acid|CS-W008333

Structure of 3222-47-7

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General Information

  • CAS No. 3222-47-7
  • Cat. No. CS-W008333
  • Purity ≥98%
  • MDL No. MFCD00006341
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇NO₂
  • Molecular Weight 137.14
  • Synonym(s) None
  • SMILES O=C(O)C1=CN=C(C)C=C1

Description

Starch is a carbohydrate reserve in plants and a major source of energy for humans. In plants, starch is found in chloroplasts of leaf and in the amyloplasts of tuber and seeds. Structurally, starch consists of two major polysaccharides, namely amylose and amylopectin. Both consists of chains of -(1,4)-linked D-glucose residues interconnected through -(1,6)-glycosidic linkages. Potato starch is superior to others, functionally, because of its low lipid level. Nutritional composition of starch comprises of rapidly digestible starch, slowly digestible starch, and resistant starch (RS). Amylases are the starch degrading enzymes. Starch digestibility affects the blood glucose levels and is controlled by factors like carbohydrate contents of foods, nutritional composition of starch and cooking foods. Inhibition of pancreatic amylase is of therapeutic importance for delaying starch digestion, to prevent postprandial hyperglycemia. Food industries use starch as thickening agent.Starch from potato has been used as a substrate for -amylase inhibition assay, by use of raw and cooked food samples and aerial parts of Trichosanthes cucumerina Linn, as a substrate to determine SusG activity, in animal gut microbiota activity using DNSA assay.

Application

6-Methylnicotinic acid serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling the construction of bioactive heterocycles and pharmaceutical scaffolds. Its pyridine core supports standard functionalization at C-2 and C-4 positions, while the methyl group enhances metabolic stability and modulates electronic properties. The carboxylic acid functionality facilitates direct coupling reactions, amide formation, or salt formation, offering excellent bench stability and ease of purification. This compound functions reliably in standard transformations relevant to API development and process optimization.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.08822
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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