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Structure of 321601-48-3
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Methyl 6-bromo-3-hydroxypyridine-2-carboxylate features a brominated pyridine core with orthogonal functional groups enabling direct coupling and derivatization. The 3-hydroxyl moiety offers hydrogen-bonding capacity, while the methyl ester facilitates selective reduction or amidation. This bench-stable scaffold integrates readily into complex heterocyclic architectures under standard conditions.
Methyl 6-bromo-3-hydroxypyridine-2-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions at the bromo position while retaining the hydroxyl group for selective derivatization. The ester functionality supports further transformations, and the molecule exhibits good bench stability, facilitating purification and integration into multi-step synthetic sequences for pharmaceutical and agrochemical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: