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CS-W001157 4
Total: USD 88.00

6-Bromo-3-methoxypicolinic acid

  • CAS No. 1256810-26-0

  • Cat. No. CS-0146023
  • Molecule weight232.03
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-Bromo-3-methoxypicolinic acid|CS-0146023

Structure of 1256810-26-0

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General Information

  • CAS No. 1256810-26-0
  • Cat. No. CS-0146023
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrNO₃
  • Molecular Weight 232.03
  • Synonym(s) 2-Pyridinecarboxylic acid,6-bromo-3-methoxy-
  • SMILES O=C(C1=NC(Br)=CC=C1OC)O

Description

6-Bromo-3-methoxypicolinic acid features a bromine substituent at the 6-position and a methoxy group at the 3-position on the picolinic acid scaffold. This combination imparts enhanced electron-withdrawing character and modulates solubility, enabling efficient incorporation into pharmaceutical intermediates and functionalized heterocycles under standard conditions.

Application

6-Bromo-3-methoxypicolinic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its bromo group enables palladium-catalyzed cross-coupling reactions, while the methoxypicolinate scaffold provides a platform for further functionalization. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   59.42
  • LogP   1.5509
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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