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Structure of 321592-49-8
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This 2-(6-cyanopyridin-2-yl)acetic acid features a pyridine ring bearing a nitrile group at the 6-position, coupled with a carboxylic acid-functionalized ethyl spacer. The electron-deficient pyridine ring enhances reactivity in conjugate addition and transition metal-catalyzed coupling processes. This structure enables integration into bioconjugation scaffolds and pharmaceutical intermediates where polarity and hydrogen-bonding capacity are critical.
2-(6-Cyanopyridin-2-yl)acetic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyridine-containing heterocycles and bioactive molecules. Its nitrile and carboxylic acid functionalities offer orthogonal reactivity for derivatization, including amidation, esterification, and nucleophilic substitution. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for iterative synthetic workflows and scale-up applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: