((1S,2S)-Cyclohexane-1,2-diyl)dimethanol

Name: ((1S,2S)-Cyclohexane-1,2-diyl)dimethanol
Brand: ChemScene
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CAS No. 3205-34-3
Cat. No. CS-0135650
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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((1S,2S)-Cyclohexane-1,2-diyl)dimethanol|CS-0135650

Structure of 3205-34-3

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General Information

CAS No. 3205-34-3
Cat. No. CS-0135650
Purity ≥98%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₆O₂
Molecular Weight 144.21
Synonym(s) 1,2-Cyclohexanedimethanol, (1S-trans)-
SMILES OC[C@@H]1[C@@H](CO)CCCC1

Description

This chiral diol features a rigid cyclohexane backbone with adjacent hydroxyl groups, enabling precise stereochemical control in asymmetric synthesis. The 1,2-diol motif facilitates selective protection and oxidation reactions, while the bench-stable nature supports reliable use in complex molecular architectures.

Application

((1S,2S)-Cyclohexane-1,2-diyl)dimethanol serves as a chiral building block for asymmetric synthesis, enabling stereoselective transformations in medicinal chemistry and natural product synthesis. Its rigid trans-diol framework provides defined stereochemistry and enhances diastereoselectivity in functionalization reactions. The molecule exhibits excellent bench stability, facilitates straightforward purification, and demonstrates broad compatibility with protecting group strategies and coupling protocols in complex molecule assembly.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

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Computational Chemistry Data

TPSA 40.46
LogP 0.7774
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 2

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Fatty ring compounds Cyclohexane compounds

Key Words

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((1S,2S)-Cyclohexane-1,2-diyl)dimethanol

CAS No. 3205-34-3

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