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CS-W001157 4
Total: USD 88.00

4-Fluorophthalic acid

  • CAS No. 320-97-8

  • Cat. No. CS-W017018
  • Purity≥97%
  • MDL No.MFCD06208213

*For research and further manufacturing use only, not for direct human use.

4-Fluorophthalic acid|CS-W017018

Structure of 320-97-8

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General Information

  • CAS No. 320-97-8
  • Cat. No. CS-W017018
  • Purity ≥97%
  • MDL No. MFCD06208213
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅FO₄
  • Molecular Weight 184.12
  • Synonym(s) None
  • SMILES O=C(C1=CC=C(F)C=C1C(O)=O)O

Description

4-Fluorophthalic acid features a fluorinated aromatic core with two carboxylic acid groups in the para configuration, enabling efficient integration into conjugated systems. This electron-deficient scaffold facilitates coupling reactions under mild conditions and enhances solubility in polar solvents. The molecule exhibits bench-stable behavior and serves as a key building block for functional materials and pharmaceutical intermediates.

Application

4-Fluorophthalic acid serves as a versatile building block in synthetic organic chemistry, enabling the construction of fluorinated heterocycles and pharmaceutical scaffolds. Its ortho-dicarboxylic acid functionality facilitates efficient cyclizations, metal coordination, and derivatization under standard conditions. The fluorine substituent enhances metabolic stability and modulates electronic properties, making it valuable for medicinal chemistry applications. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step syntheses.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   74.6
  • LogP   1.2221
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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