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CS-W001157 4
Total: USD 88.00

L-Homocysteine thiolactone hydrochloride

  • CAS No. 31828-68-9

  • Cat. No. CS-6394
  • Purity≥98%
  • MDL No.MFCD00065494

*For research and further manufacturing use only, not for direct human use.

L-Homocysteine thiolactone hydrochloride|CS-6394

Structure of 31828-68-9

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General Information

  • CAS No. 31828-68-9
  • Cat. No. CS-6394
  • Purity ≥98%
  • MDL No. MFCD00065494
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₈ClNOS
  • Molecular Weight 153.63
  • Synonym(s) None
  • SMILES N[C@@H](CCS1)C1=O.Cl

Application

L-Homocysteine thiolactone (hydrochloride) serves as a key building block for cysteine-containing peptides and thiol-directed conjugation strategies. Its reactive thiolactone ring enables site-specific derivatization under mild conditions, facilitating the synthesis of bioconjugates and peptidomimetics. The hydrochloride salt enhances solubility and bench stability, simplifying handling and purification in synthetic workflows.

Synthesis

  • Route1
    • null|null
      1051970-96-7
    • ~%
    • In-stock
      L-Homocysteine thiolactone hydrochloride|CS-6394
      31828-68-9

    References

    • EP1964838 A1, ; Page/Page column 5 ;
  • Route2
    • null|null
      1051970-97-8
    • ~%
    • In-stock
      L-Homocysteine thiolactone hydrochloride|CS-6394
      31828-68-9

    References

    • EP1964838 A1, ; Page/Page column 5 ;
  • Route3

    References

    • WO2010/148191 A2, ; Page/Page column 45-49; 63 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   43.09
  • LogP   0.399
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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