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CS-W001157 4
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Ethyl 5-amino-2-methylthiazole-4-carboxylate

  • CAS No. 31785-05-4

  • Cat. No. CS-W016895
  • Purity≥97%
  • MDL No.MFCD07357418

*For research and further manufacturing use only, not for direct human use.

Ethyl 5-amino-2-methylthiazole-4-carboxylate|CS-W016895

Structure of 31785-05-4

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General Information

  • CAS No. 31785-05-4
  • Cat. No. CS-W016895
  • Purity ≥97%
  • MDL No. MFCD07357418
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀N₂O₂S
  • Molecular Weight 186.23
  • Synonym(s) 4-Thiazolecarboxylic acid, 5-amino-2-methyl-, ethyl ester
  • SMILES CCOC(=O)C1=C(N)SC(C)=N1

Description

Ethyl 5-amino-2-methylthiazole-4-carboxylate features a reactive amino group flanked by electron-rich thiazole and ester functionalities, enabling direct incorporation into heterocyclic scaffolds. This bench-stable, moisture-tolerant building block streamlines synthesis of bioactive thiazole derivatives in medicinal chemistry workflows.

Application

Ethyl 5-amino-2-methylthiazole-4-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted thiazoles and medicinally relevant scaffolds. The amino and ester functionalities offer orthogonal reactivity for sequential derivatization, while the methyl group enhances regiochemical control. Bench-stable and readily purified by crystallization, it functions effectively in coupling reactions, cyclizations, and transition-metal-catalyzed transformations common in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   65.21
  • LogP   1.21042
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   2

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