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Structure of 312904-49-7
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This bench-stable dihydrochloride salt features a fluorinated pyridine core paired with a primary amine functionality, enabling efficient coupling in medicinal chemistry. The para-fluorine substitution enhances electrophilic reactivity, while the protonated amine ensures solubility and compatibility in aqueous reaction media.
(3-Fluoropyridin-2-yl)methanamine dihydrochloride serves as a versatile building block in medicinal chemistry, enabling the construction of fluorinated pyridine-containing scaffolds prevalent in kinase inhibitors and CNS-active compounds. The dihydrochloride salt enhances solubility and stability for handling, while the primary amine functionality facilitates straightforward coupling reactions, reductive amination, and amide bond formation under standard conditions. Its ortho-fluoro substitution pattern supports directed metalation and selective functionalization, making it a practical choice for iterative synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: