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CS-W001157 4
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2-(3-Oxocyclopentyl)acetic acid

  • CAS No. 3128-05-0

  • Cat. No. CS-0145408
  • Purity≥95%
  • MDL No.MFCD00154377

*For research and further manufacturing use only, not for direct human use.

2-(3-Oxocyclopentyl)acetic acid|CS-0145408

Structure of 3128-05-0

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General Information

  • CAS No. 3128-05-0
  • Cat. No. CS-0145408
  • Purity ≥95%
  • MDL No. MFCD00154377
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀O₃
  • Molecular Weight 142.15
  • Synonym(s) 3-Oxo-cyclopentaneacetic acid
  • SMILES O=C(CC1CC(CC1)=O)O

Description

This cyclopentyl-containing carboxylic acid features a ketone-functionalized side chain, enabling direct incorporation into synthetic scaffolds. The molecule combines structural rigidity from the cyclopentane ring with reactive carbonyl and carboxylate handles, facilitating downstream derivatization in medicinal chemistry and materials synthesis.

Application

2-(3-Oxocyclopentyl)acetic acid serves as a versatile building block for cyclopentane-containing scaffolds, enabling efficient access to bioactive molecules through standard functional group manipulations. Its α-ketoacid motif facilitates enantioselective transformations and acts as a precursor in heterocycle synthesis. The molecule exhibits good bench stability and is compatible with common protecting group strategies, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.

Synthesis

  • Route1
    • null|null
      92731-03-8
    • ~66%
    • In-stock
      2-(3-Oxocyclopentyl)acetic acid|CS-0145408
      3128-05-0

    References

    • Yamane, Hisakazu; Sugawara, Jun; Suzuki, Yasushi; Shimamura, Etsuko; Takahashi, Nobutaka Agricultural and Biological Chemistry, 1980 , vol. 44, # 12 p. 2857 - 2864
  • Route2

    References

    • Iguchi, Mayu; Doi, Hirohisa; Hata, Seiji; Tomioka, Kiyoshi Chemical and Pharmaceutical Bulletin, 2004 , vol. 52, # 1 p. 125 - 129
  • Route3
    • null|null
      679836-06-7
    • ~%
    • In-stock
      2-(3-Oxocyclopentyl)acetic acid|CS-0145408
      3128-05-0

    References

    • Iguchi, Mayu; Doi, Hirohisa; Hata, Seiji; Tomioka, Kiyoshi Chemical and Pharmaceutical Bulletin, 2004 , vol. 52, # 1 p. 125 - 129

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3265
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   54.37
  • LogP   0.8303
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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