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CS-W001157 4
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5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

  • CAS No. 312753-53-0

  • Cat. No. CS-W020205
  • Purity≥98%
  • MDL No.MFCD13185940

*For research and further manufacturing use only, not for direct human use.

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride|CS-W020205

Structure of 312753-53-0

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General Information

  • CAS No. 312753-53-0
  • Cat. No. CS-W020205
  • Purity ≥98%
  • MDL No. MFCD13185940
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₀ClN
  • Molecular Weight 225.76
  • Synonym(s) 5,6-Diethyl-2,3-dihydro-1H-inden-2-amine HCl
  • SMILES [H]Cl.NC1CC2=C(C1)C=C(C(CC)=C2)CC

Description

This bench-stable indenamine derivative features two ethyl substituents at the 5,6-positions, enhancing lipophilicity and metabolic stability. The protonated amine group ensures water solubility and facilitates salt formation, enabling efficient handling in synthetic workflows.

Application

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride serves as a stable, bench-ready building block for indoline-based scaffolds. Its amine functionality enables straightforward derivatization in amide coupling, reductive amination, and electrophilic substitution reactions. The diethyl substitution enhances lipophilicity and metabolic stability, making it suitable for medicinal chemistry campaigns targeting CNS-active compounds. The hydrochloride salt improves solubility and handling, facilitating purification and integration into standard synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.6591
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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