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CS-W001157 4
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4-(4-Formyl-3-methoxyphenoxy)butanoic acid

  • CAS No. 309964-23-6

  • Cat. No. CS-D0567
  • Purity≥96%
  • MDL No.MFCD01317807

*For research and further manufacturing use only, not for direct human use.

4-(4-Formyl-3-methoxyphenoxy)butanoic acid|CS-D0567

Structure of 309964-23-6

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General Information

  • CAS No. 309964-23-6
  • Cat. No. CS-D0567
  • Purity ≥96%
  • MDL No. MFCD01317807
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₄O₅
  • Molecular Weight 238.24
  • Synonym(s) Butanoic acid, 4-(4-formyl-3-methoxyphenoxy)-
  • SMILES COC1=C(C=CC(OCCCC(O)=O)=C1)C=O

Description

This butanoic acid derivative features a para-formylated phenoxy moiety with a methoxy substituent, enabling conjugation via aldehyde functionalization. The extended aliphatic chain provides flexibility for linker integration in bioconjugation and materials applications.

Application

4-(4-Formyl-3-methoxyphenoxy)butanoic acid serves as a versatile building block for bioactive molecule synthesis, featuring a pendant aldehyde and carboxylic acid for orthogonal functionalization. The methoxy-substituted aromatic ring enhances metabolic stability, while the flexible butanoyl linker enables conjugation in peptide and macrocyclic scaffolds. Bench-stable and amenable to standard purification methods, it facilitates efficient derivatization via reductive amination, amidation, or coupling reactions in medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   72.83
  • LogP   1.7513
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   7

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