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CS-W001157 4
Total: USD 88.00

5-(4-Formyl-3,5-dimethoxyphenoxy)pentanoic acid

  • CAS No. 115109-59-6

  • Cat. No. CS-0539843
  • Purity≥98%
  • MDL No.MFCD08062387

*For research and further manufacturing use only, not for direct human use.

5-(4-Formyl-3,5-dimethoxyphenoxy)pentanoic acid|CS-0539843

Structure of 115109-59-6

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General Information

  • CAS No. 115109-59-6
  • Cat. No. CS-0539843
  • Purity ≥98%
  • MDL No. MFCD08062387
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₈O₆
  • Molecular Weight 282.29
  • Synonym(s) 4-formyl-3,5-dimethoxyphenoxyvaleric acid
  • SMILES COC1=CC(=CC(=C1C=O)OC)OCCCCC(=O)O

Description

This boronic acid derivative features a pendant aldehyde group flanked by two methoxy substituents, enabling orthogonal reactivity in conjugation workflows. The extended pentanoic acid chain enhances solubility and provides a flexible spacer for bioconjugation applications.

Application

5-(4-Formyl-3,5-dimethoxyphenoxy)pentanoic acid serves as a versatile bifunctional building block for the synthesis of bioactive scaffolds. The aldehyde and carboxylic acid functionalities enable sequential conjugation via reductive amination or amide bond formation, respectively. Its bench-stable nature and compatibility with common protecting group strategies facilitate integration into complex molecule assembly workflows.

Synthesis

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    • In-stock
      5-(4-Formyl-3,5-dimethoxyphenoxy)pentanoic acid|CS-0539843
      115109-59-6

    References

    • Novo Nordisk A/S Patent: US5977178 A1, 1999 ;
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    References

    • Albericio; Kneib-Cordonier; Biancalana; Gera; Masada; Hudson; Barany Journal of Organic Chemistry, 1990 , vol. 55, # 12 p. 3730 - 3743
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    References

    • Albericio; Kneib-Cordonier; Biancalana; Gera; Masada; Hudson; Barany Journal of Organic Chemistry, 1990 , vol. 55, # 12 p. 3730 - 3743

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   82.06
  • LogP   2.15
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   9

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