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CS-W001157 4
Total: USD 88.00

3-Methoxycyclobutan-1-one

  • CAS No. 30830-25-2

  • Cat. No. CS-0051289
  • Purity≥97%
  • MDL No.MFCD20266830

*For research and further manufacturing use only, not for direct human use.

3-Methoxycyclobutan-1-one|CS-0051289

Structure of 30830-25-2

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General Information

  • CAS No. 30830-25-2
  • Cat. No. CS-0051289
  • Purity ≥97%
  • MDL No. MFCD20266830
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈O₂
  • Molecular Weight 100.12
  • Synonym(s) 3α-Methoxycyclobutanone
  • SMILES COC1CC(=O)C1

Description

3-Methoxycyclobutan-1-one is a cyclic ketone featuring a methoxy group at the 3-position, offering enhanced solubility and stability in polar reaction media. This functionalized cyclobutane scaffold serves as a key building block for synthesizing bioactive molecules and specialty polymers under standard conditions.

Application

3-Methoxycyclobutan-1-one serves as a versatile synthon in synthetic organic chemistry, enabling efficient construction of substituted cyclobutane scaffolds. Its electrophilic carbonyl and adjacent methoxy group facilitate regioselective functionalization, including nucleophilic additions and enolate-mediated transformations. The compound exhibits good bench stability and compatibility with common protecting group strategies, making it a practical choice for medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H225-H315-H319-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   0.3643
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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