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Structure of 30652-11-0
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3-Hydroxy-1,2-dimethyl-4(1H)-pyridone (Hdpp, Deferiprone) is a hydroxy ketone derivative. It reacts with uranyl salts [UO2(NO3)2] in aqueous acidic solution to afford mono nuclear complexes ([UO2(dpp)(Hdpp)2(H2O)]ClO4). X-ray studies have been conducted to examine the structure and geometry of these complexes.3-Hydroxy-1,2-dimethyl-4(1H)-pyridone (OH-pyridone) may be used in the bacterial killing assays. It has been employed as hydroxyketone chelating agent and its cytotoxic action against oral human normal and tumor cell lines has been evaluated.
Deferiprone serves as a potent iron-chelating agent with established utility in the management of iron overload disorders. Its 3-hydroxy-1,2-diketone scaffold enables high-affinity binding to Fe³⁺, facilitating selective metal complexation under physiological conditions. The compound exhibits favorable solubility and oral bioavailability, supporting its use in clinical and preclinical settings. Deferiprone functions effectively in both aqueous and organic media, enabling integration into diverse synthetic workflows involving metal coordination or redox modulation.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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