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Structure of 305448-92-4
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N-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamide features a boronate ester group flanked by tetramethyl-substituted dioxaborolane rings, enabling stable coupling in Suzuki-Miyaura reactions. The methanesulfonamide moiety provides enhanced solubility and metabolic stability. This compound serves as a key building block for bioactive molecule synthesis.
N-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamide serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylboronate group enables efficient coupling with aryl and heteroaryl halides under mild conditions, offering excellent functional group tolerance and bench stability. Its methanesulfonamide handle provides a polar, robust amine surrogate suitable for downstream derivatization in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: