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CS-W001157 4
Total: USD 88.00

S-Acetylglutathione

  • CAS No. 3054-47-5

  • Cat. No. CS-0144319
  • Purity≥96%
  • MDL No.MFCD09952588

*For research and further manufacturing use only, not for direct human use.

S-Acetylglutathione|CS-0144319

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General Information

  • CAS No. 3054-47-5
  • Cat. No. CS-0144319
  • Purity ≥96%
  • MDL No. MFCD09952588
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₉N₃O₇S
  • Molecular Weight 349.36
  • Synonym(s) None
  • SMILES O=C(O)CNC([C@H](CSC(C)=O)NC(CC[C@@H](C(O)=O)N)=O)=O

Description

S-Acetylglutathione delivers a stabilized, bioavailable form of glutathione with enhanced cellular permeability. This acetylated derivative resists premature degradation in the gastrointestinal tract and maintains redox activity under physiological conditions. Designed for sustained intracellular delivery, it supports antioxidant defense and metabolic resilience in challenging biological environments.

Application

S-Acetylglutathione serves as a stable, bioavailable form of glutathione, enabling efficient cellular delivery of reduced glutathione without susceptibility to enzymatic degradation. It functions as a key thiol-containing antioxidant precursor, facilitating redox homeostasis and supporting detoxification pathways. Its acetylated cysteine moiety enhances membrane permeability and metabolic stability, making it valuable in oxidative stress research and therapeutic formulation development.

Synthesis

  • Route1

    References

    • POLYINTELL Patent: US2010/234565 A1, 2010 ;
  • Route2

    References

    • Brick; Jesse Chemistry and Industry (London, United Kingdom), 1954 , p. 1513
  • Route3

    References

    • Kielley; Bradley Journal of Biological Chemistry, 1954 , vol. 206, p. 327

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   175.89
  • LogP   -1.8562
  • H_Acceptors   7
  • H_Donors   5
  • Rotatable_Bonds   10

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