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CS-W001157 4
Total: USD 88.00

2,6-Dichloro-4-methoxybenzonitrile

  • CAS No. 30482-87-2

  • Cat. No. CS-0529701
  • Molecule weight202.04
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,6-Dichloro-4-methoxybenzonitrile|CS-0529701

Structure of 30482-87-2

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General Information

  • CAS No. 30482-87-2
  • Cat. No. CS-0529701
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅Cl₂NO
  • Molecular Weight 202.04
  • Synonym(s) 2.6-Dichlor-4-fluorsulfonyl-phenol
  • SMILES N#CC1=C(Cl)C=C(OC)C=C1Cl

Description

2,6-Dichloro-4-methoxybenzonitrile features a trifunctional aromatic core with electron-withdrawing nitrile and dichloro substituents flanking a methoxy group. This configuration imparts enhanced stability and tailored reactivity for use in pharmaceutical intermediates and agrochemical synthesis under standard conditions.

Application

2,6-Dichloro-4-methoxybenzonitrile serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of heterocyclic scaffolds via nucleophilic aromatic substitution. Its dichloro substitution pattern provides orthogonal reactivity for sequential functionalization, while the methoxy and nitrile groups offer excellent compatibility with standard coupling protocols and facilitate downstream derivatization. The compound exhibits high bench stability and is readily purified by recrystallization, supporting scalable synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   33.02
  • LogP   2.87368
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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