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CS-W001157 4
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N-(2-cyanophenyl)pyridine-2-carboxamide

  • CAS No. 304650-02-0

  • Cat. No. CS-W001530
  • Molecule weight223.23
  • Purity≥98%
  • MDL No.MFCD02128063

*For research and further manufacturing use only, not for direct human use.

N-(2-cyanophenyl)pyridine-2-carboxamide|CS-W001530

Structure of 304650-02-0

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General Information

  • CAS No. 304650-02-0
  • Cat. No. CS-W001530
  • Purity ≥98%
  • MDL No. MFCD02128063
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₉N₃O
  • Molecular Weight 223.23
  • Synonym(s) N-(2-Cyanophenyl)picolinamide
  • SMILES N#CC1=CC=CC=C1N=C(O)C2=CC=CC=N2

Description

N-(2-cyanophenyl)pyridine-2-carboxamide features a dual heterocyclic scaffold integrating a nitrile group and amide functionality, enabling strong coordination in metal-ligand systems. This structural motif enhances planarity and electron delocalization, supporting applications in organic electronics and catalytic ligand design.

Application

N-(2-cyanophenyl)pyridine-2-carboxamide serves as a versatile building block in medicinal chemistry, enabling the construction of biologically relevant heterocyclic scaffolds. Its dual functionality—nitrile and amide groups—facilitates diverse transformations, including cyclizations and metal-catalyzed couplings. The molecule exhibits good bench stability and compatibility with standard purification techniques, making it well-suited for iterative synthesis workflows in API development.

Synthesis

  • Route1
    • null|null
      109-04-6
    • In-stock
      2-Aminobenzonitrile|CS-W013598
      1885-29-6
    • null|null
      13939-06-5
    • ~49%
    • In-stock
      N-(2-cyanophenyl)pyridine-2-carboxamide|CS-W001530
      304650-02-0

    References

    • Wu, Xiao-Feng; Oschatz, Stefan; Sharif, Muhammad; Beller, Matthias; Langer, Peter Tetrahedron, 2014 , vol. 70, # 1 p. 23 - 29

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P264-P270-P280-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   69.27
  • LogP   2.58958
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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