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CS-W001157 4
Total: USD 88.00

3,3'-Disulfanediylbis(propan-1-ol)

  • CAS No. 30453-21-5

  • Cat. No. CS-0162834
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3,3'-Disulfanediylbis(propan-1-ol)|CS-0162834

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General Information

  • CAS No. 30453-21-5
  • Cat. No. CS-0162834
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₄O₂S₂
  • Molecular Weight 182.30
  • Synonym(s) Fudosteine Impurity 18
  • SMILES OCCCSSCCCO

Description

This bifunctional thiol compound features two sulfhydryl groups linked by a disulfide bridge, each attached to a propan-1-ol moiety. The structure enables reversible conjugation in redox-sensitive systems, offering stable yet cleavable linkages under physiological conditions. Ideal for bioconjugation workflows requiring controlled release or site-specific immobilization.

Application

3,3'-Disulfanediylbis(propan-1-ol) serves as a versatile bifunctional thiol building block, enabling the construction of disulfide-linked scaffolds in synthetic organic chemistry. Its two primary hydroxyl groups provide enhanced solubility and facilitate purification, while the terminal thiols offer reliable reactivity in thiol-disulfide exchange reactions. The molecule demonstrates good bench stability and functions effectively in the synthesis of redox-active compounds, peptide conjugates, and functionalized polymers under standard laboratory conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H302-H315-H319-H335
Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P403-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   1.1326
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   7

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