6-Bromoimidazo[1,2-a]pyridine-3-carbaldehyde

Name: 6-Bromoimidazo[1,2-a]pyridine-3-carbaldehyde
Brand: ChemScene
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CAS No. 30384-96-4
Cat. No. CS-W022471
Purity≥98%
MDL No.MFCD09864909

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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6-Bromoimidazo[1,2-a]pyridine-3-carbaldehyde|CS-W022471

Structure of 30384-96-4

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General Information

CAS No. 30384-96-4
Cat. No. CS-W022471
Purity ≥98%
MDL No. MFCD09864909
Storage -20°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₅BrN₂O
Molecular Weight 225.04
Synonym(s) 6-BROMOIMIDAZO[1,2-A]PYRIDINE-3-CARBOXALDEHYDE
SMILES BrC2=C[N]1C(=NC=C1C=O)C=C2

Description

6-Bromoimidazo[1,2-a]pyridine-3-carbaldehyde features a brominated imidazopyridine core paired with a reactive aldehyde group, enabling direct functionalization in cross-coupling and conjugation workflows. The electron-deficient heterocycle enhances compatibility with nucleophilic attack, while the aldehyde facilitates rapid derivatization under mild conditions. This scaffold delivers high stability and predictable reactivity in synthetic medicinal chemistry and materials development.

Application

6-Bromoimidazo[1,2-a]pyridine-3-carbaldehyde serves as a versatile building block for heterocyclic synthesis, enabling efficient construction of pharmacologically relevant scaffolds. Its bromo and aldehyde functionalities provide orthogonal handles for Pd-catalyzed cross-coupling and condensation reactions, facilitating rapid diversification in medicinal chemistry campaigns. The compound exhibits good bench stability and is amenable to standard purification techniques, making it well-suited for high-throughput synthetic workflows.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 34.37
LogP 1.9093
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Key Words

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6-Bromoimidazo[1,2-a]pyridine-3-carbaldehyde

CAS No. 30384-96-4

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