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CS-W001157 4
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2-Bromo-5-nitrothiazole

  • CAS No. 3034-48-8

  • Cat. No. CS-W001966
  • Purity≥95%
  • MDL No.MFCD00005317

*For research and further manufacturing use only, not for direct human use.

2-Bromo-5-nitrothiazole|CS-W001966

Structure of 3034-48-8

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General Information

  • CAS No. 3034-48-8
  • Cat. No. CS-W001966
  • Purity ≥95%
  • MDL No. MFCD00005317
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃HBrN₂O₂S
  • Molecular Weight 209.02
  • Synonym(s) 4-27-00-00963 (Beilstein Handbook Reference)
  • SMILES [O-][N+](=O)c1cnc(s1)Br

Description

6-((tert-Butoxycarbonyl)amino)hexyl 4-methylbenzenesulfonate is a six carbon linker containing a tosyl group and Boc-protected amine group. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form a free amine.

Synthesis

  • Route1

    References

    • Kim, Yong Hae Phosphorus, Sulfur and Silicon and the Related Elements, 1993 , vol. 74, # 1-4 p. 249 - 260
  • Route2
    • In-stock
      Enheptin|CS-0030564
      121-66-4
    • null|null
      71-41-0
    • ~61%
    • In-stock
      2-Bromo-5-nitrothiazole|CS-W001966
      3034-48-8

    References

    • Sugen, Inc. Patent: US6080772 A1, 2000 ; US 6080772 A
  • Route3

    References

    • Journal fuer Praktische Chemie (Leipzig), , vol. 316, p. 349 - 352

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   56.03
  • LogP   1.8138
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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