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CS-W001157 4
Total: USD 88.00

3-Chloropyrrolo[1,2-a]pyrazine

  • CAS No. 3029582-95-1

  • Cat. No. CS-1097840
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Chloropyrrolo[1,2-a]pyrazine|CS-1097840

Structure of 3029582-95-1

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General Information

  • CAS No. 3029582-95-1
  • Cat. No. CS-1097840
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅ClN₂
  • Molecular Weight 152.58
  • Synonym(s) None
  • SMILES ClC1=CN2C(C=N1)=CC=C2

Description

3-Chloropyrrolo[1,2-a]pyrazine is a heteroaromatic scaffold featuring a chlorine atom at the 3-position, enabling direct functionalization in cross-coupling reactions. This electron-deficient core integrates readily into bioactive molecules, offering enhanced metabolic stability and improved solubility profiles in medicinal chemistry applications.

Application

3-Chloropyrrolo[1,2-a]pyrazine serves as a versatile heterocyclic building block for medicinal chemistry and materials science. The chloro substituent enables direct functionalization via palladium-catalyzed cross-coupling reactions, facilitating the construction of biologically active scaffolds. Its planar, electron-deficient core enhances π-stacking interactions in target binding, while excellent bench stability supports reliable handling in multi-step syntheses.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   17.3
  • LogP   1.9877
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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