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CS-W001157 4
Total: USD 88.00

3-Phenoxyazetidine hydrochloride

  • CAS No. 301335-39-7

  • Cat. No. CS-0072870
  • Molecule weight185.65
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Phenoxyazetidine hydrochloride|CS-0072870

Structure of 301335-39-7

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General Information

  • CAS No. 301335-39-7
  • Cat. No. CS-0072870
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂ClNO
  • Molecular Weight 185.65
  • Synonym(s) 3-Phenoxy-azetidinehydrochloride
  • SMILES C1(CNC1)OC2=CC=CC=C2.Cl

Description

3-Phenoxyazetidine hydrochloride is a bench-stable, moisture-tolerant heterocyclic building block featuring a phenoxy-substituted azetidine core. This compound integrates readily into medicinal chemistry campaigns, delivering enhanced metabolic stability and improved solubility in polar reaction media. Its protonated form ensures efficient handling and compatibility with standard synthetic workflows.

Application

3-Phenoxyazetidine hydrochloride serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through established coupling and functionalization protocols. Its azetidine core provides enhanced metabolic stability and improved target engagement compared to larger ring systems, while the phenoxy group offers favorable lipophilicity and hydrogen-bonding capacity. The hydrochloride salt ensures excellent bench stability, ease of handling, and compatibility with standard purification techniques in multi-step synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   1.459
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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